منابع مشابه
Imaging Islet Cell Tumours
Islet cell tumours are rare lesions. The majority (85%) are functioning hormone-producing tumours, insulinomas and gastrinomas being the most common. Approximately 15% of islet cell tumours are nonfunctioning. These are usually larger lesions, often presenting at an advanced stage as a pancreatic mass or with metastatic disease. This review will focus on the role of endoscopic ultrasound in the...
متن کاملThe islet ghrelin cell.
The islets of Langerhans are key regulators of glucose homeostasis and have been known as a structure for almost one and a half centuries. During the twentieth century several different cell types were described in the islets of different species and at different developmental stages. Six cell types with identified hormonal product have been described so far by the use of histochemical staining...
متن کاملIslet cell tumours
Islet cells tumours are a range of rare neoplasms of neuroendocrine origin arising in or close to the pancreas. The normal islet cells of Langerhans in the pancreas contain B-cells (which secrete insulin), A-cells (which secrete glucagon), D-cells (which secrete somatostatin), Dl-cells (which secrete pancreatic polypeptide, PP) and D2-cells (which secrete vasoactive intestinal peptide). The maj...
متن کاملIntra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation
The intra-islet microvasculature is a critical interface between the blood and islet endocrine cells governing a number of cellular and pathophysiological processes associated with the pancreatic tissue. A growing body of evidence indicates a strong functional and physical interdependency of β-cells with endothelial cells (ECs), the building blocks of islet microvasculature. Intra-islet ECs, ac...
متن کاملIslet encapsulation: strategies to enhance islet cell functions.
Diabetes is one of the most prevalent, costly, and debilitating diseases in the world. Although traditional insulin therapy has alleviated the short-term effects, long-term complications are ubiquitous and harmful. For these reasons, alternative treatment options are being developed. This review investigates one appealing area: cell replacement using encapsulated islets. Encapsulation materials...
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ژورنال
عنوان ژورنال: SCIENTIA SINICA Vitae
سال: 2018
ISSN: 1674-7232
DOI: 10.1360/n052018-00163